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2 article(s) from Riekstina, Una

Nanoparticle delivery to metastatic breast cancer cells by nanoengineered mesenchymal stem cells

Liga Saulite,
Karlis Pleiko,
Ineta Popena,
Dominyka Dapkute,
Ricardas Rotomskis and
Una Riekstina

Beilstein J. Nanotechnol. 2018, 9, 321–332, doi:10.3762/bjnano.9.32

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Figure 1: Characterisation of the optimal quantum dot (QD) incubation conditions in mesenchymal stem cells (M...

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Figure 2: Characterisation of mesenchymal stem cells (MSCs) in 3D culture conditions. (A) MSC spheroid format...

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Figure 3: The dynamics of quantum dot (QD) signal in mesenchymal stem cells (MSCs) 3D culture. Representative...

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Figure 4: Comparison of MCF7 and MDA-MB-231 properties in 2D and 3D culture conditions. (A) The morphology of...

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Figure 5: The viability of mesenchymal stem cells (MSCs), MCF7 and MDA-MB-231 cells in spheroids. The viabili...

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Figure 6: Quantum dot (QD) uptake in MCF7 and MDA-MB-231 cells in 3D co-culture. (A) Morphology of MSC/MCF7 a...

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Figure 7: Fluorescence imaging of quantum dot (QD) intracellular accumulation in MCF7 and MDA-MB-231 cells du...

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Full Research Paper

Published 29 Jan 2018

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Nano-engineered skin mesenchymal stem cells: potential vehicles for tumour-targeted quantum-dot delivery

Liga Saulite,
Dominyka Dapkute,
Karlis Pleiko,
Ineta Popena,
Simona Steponkiene,
Ricardas Rotomskis and
Una Riekstina

Beilstein J. Nanotechnol. 2017, 8, 1218–1230, doi:10.3762/bjnano.8.123

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Figure 1: The concentration-dependent effect of QDs on the viability of MSCs. Viability was measured by a col...

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Figure 2: Evaluation of the optimal QD uptake conditions in skin MSCs. Time-dependent (a) and concentration-d...

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Figure 3: The release of QDs from MSCs. (a) QD loss in complete medium (FBS +) and serum-free medium (FBS −) ...

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Figure 4: Representative data on the impact of QDs on immunophenotype and proliferation of MSCs. (a) Characte...

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Figure 5: Differentiation of MSCs into adipocytes, chondrocytes and osteocytes. Oil Red O staining of cells i...

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Figure 6: Quantification of osteogenesis and chondrogenesis in MSCs. Absorbance of Alizarin Red S (a) and Alc...

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Figure 7: QD endocytic pathway in MSCs. QD uptake pathway in MSCs labelled with QDs in complete medium (a) or...

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Figure 8: QD co-localization with endosomal compartments. Three overlaid channels represent the nucleus (blue...

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Full Research Paper

Published 07 Jun 2017

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